Caspian Journal of Dental Research

8-12

Authors: Tahereh Nosratzehi , Fateme Arbabi-Kalati * , Zohreh Arefpoor

Introduction: Oral lichen planus (OLP) is a chronic immunological disorder with unknown etiology. Some studies have reported an association between oral lichen planus and diabetes mellitus. The aim of this study was to compare the frequency of diabetes mellitus in patients with oral lichen planus and healthy persons. Materials &Methods: This case‒control study was performed on 50 patients with OLP and 50 healthy individuals. Diagnosis of OLP was confirmed by typical clinical and histopathological findings. The control group were selected randomly from healthy individuals after matching for age and sex. Blood samples were taken to achieve 5 mL for measuring fasting serum blood glucose and HbA1C. Data were analyzed using Student’s t-test. Results: In this case‒control study, 50 patients with OLP (39 females, 11 males) with a mean age of 44.5±13.24 years and 50 healthy individuals (33 females, 17 males) with a mean age of 41.3±11.44 years were evaluated. The mean fasting blood glucose and HbA1C levels in patient with OLP were 95.1±8.1 and 5.1±1.3 mg/dL, and 89.1±7.7 and 4.6±1.1 mg/dL in healthy individuals (P=1). Conclusion: The frequency of diabetes mellitus was not significantly different between the case and the control groups. The results showed that diabetes mellitus does not have a direct role in the OLP etiology.

20-26

Authors: Leila Pishevar , Shirin Zahra Farhad , Mahboubeh Mirzakhani *, Navid Haghayegh , Mohammadreza Ansarinejad

Introduction: Nowadays, several casein components such as casein phosphopeptide amorphous calcium phosphate (CPP-ACP) are vastly considered as a suitable replacement for fluoride component. The aim of this study was to compare the effect of CPP-ACP paste and fluoride varnish on dentin hypersensitivity reduction. Materials & Methods: In this clinical trial study, thirty adult patients between the ages of 20-50 years, presenting with the chief complaint of dentin hypersensitivity were examined. The loss of dentin was less than 0.5mm. The subjects divided into three groups: In groups I and II, patients were treated using CPP-ACP and fluoride varnish following manufacturer instructions. Group III received placebo gel. A visual analog scale was used to assess subjects' response to compressed air and ice stimuli at baseline, 7 days, 28 days and 60 days after treatment. Data was analyzed by One Way Analysis of Variance (ANOVA), Duncan Post Hoc test using the SPSS software version 21. Results: The results showed significant statistical difference between the groups (P<0.05). In fluoride varnish group and CPP-ACP paste group, the dentin hypersensitivity significantly decreased when baseline scores compared to post treatment scores at 7, 28, 60 days (P<0.05). There was no significant statistical difference in dentin hypersensitivity reduction in fluoride varnish and CPP-ACP paste groups. Conclusion: The results of this study showed that both of fluoride varnish and CPP-ACP paste effectively reduced dentinal hypersensitivity compared with placebo-control group.

33-39

Authors: Hamideh Kadeh, Shirin Saravani*, Babak Moradbeiki

Introduction: The geographical distribution of head and neck cancer shows considerable variation and it is site dependent. The review of the literature shows few data concerning the head and neck cancer patterns in Iran. The purpose of this study was to represent epidemiological aspects of head and neck cancers in south east of Iran. Materials &Methods: In this retrospective study, from a total of 924 diagnosed patients with cancer in the pathology department of dentistry school archives and two main hospitals in south east of Iran during 2006-2012, 287 cases of head and neck cancer were diagnosed histopathologically. Demographic data of patients such as age, gender, location and type of cancer (carcinoma, sarcoma, melanoma, metastatic, or primary) were obtained from patients’ records. Data were analyzed by SPSS statistical software (V.21) using the chi-square test. Results: Squamous cell carcinoma (39.7%) and basal cell carcinoma (26.8%) were the most common malignancies in the head and neck region. The mean age of the patients was 56.1±12.8 years and the relationship between age groups and head and neck cancers was not statistically significant (P=0.085). Male to female ratio was 0.9 to 1. The relationship between gender and types of head and neck cancers was not statistically significant. (P=0.114) Conclusion: In this study, prevalence of head and neck cancer in south east of Iran (Zahedan) was relatively high. However, comparison between findings of our study with other studies shows a relation consistency.

44-49

Authors: Parichehr Ghalayani, Mina Hamian, Maryam Jafari, Samira Hajisadeghi*

Ameloblastic fibroma is a relatively rare benign odontogenic tumor with two neoplastic components; both epithelial and ectomesenchymal. A 10-year-old girl was referred to a dentist for routine dental treatments for evaluation of the distance between mandibular right first permanent molar and mandibular right second deciduous molar and it was associated with an undesirable backward movement of erupted mandibular right first permanent molar and forward movement of mandibular right second deciduous molar. The lesion was enucleated and the material was sent for histopathologic examination. Microscopically, it was composed of neoplastic proliferation of odontogenic epithelium consisted of cords and islands in a cell-rich mesenchymal stroma, with histopathological diagnosis of ameloblastic fibroma. After 24 months of follow-up, no recurrence was observed and the mandibular right first molar was spontaneously aligned. Early diagnosis and proper management will prevent comprehensive orthodontic treatment.