Antimicrobial Property of Crude Ethanolic Extract of Mucuna pruriens leaves on Pseudomonas aeruginosa, Salmonella typhi and Shigella dysentriae
Authors: *Abraham, O.J.1, Nwobodo, A.H.2, Ngwu, B.A.F.3, Onwuatuegwu, J. T.C.4, Egbunu, Z.K.1, Yahaya, O.1, Amodu, A.E.1, Onuh, I.5 and Salihu, A. M.1.
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Mucuna pruriens also called velvet bean belongs to the family fabaceae. It is used in traditional medicine to cure worms infestation, dysentery, diarrhoea, snake bite, sexual debility, cough, tuberculosis and diabetes. This research was carried out to determine the antimicrobial activity of crude ethanolic extract of Mucuna pruriens leaves on Pseudomonas aeruginosa, Salmonella typhi, and Shigella dysenteriae. Agar well diffusion method was used to study the effect of the plant on the organisms at 300mg/ml, 400mg/ml and 500mg/ml. The Minimum Inhibitory Concentration (MIC) on each organism was 300mg/ml. At the concentration of 300mg/ml the mean zone of inhibition was 10mm, 13mm, and 13mm for Pseudomonas aeruginosa, Salmonella typhi, and Shigella dysenteriae respectively. At 400mg/ml, the mean ZI were 11mm, 18mm and 14 respectively, while at 500mg/ml, the mean ZI were 15mm, 20mm and 20mm on the organisms respectively. The zone of inhibition increased with concentration used. The result obtained showed that this plant could be further studied as alternative means to cure the ailment caused by the aforementioned microorganisms. Therefore, further studies have to be done using other solvents extraction.