Acute myocardial infarction is one of the commonest diseases and the leading cause of death for both men and women all over the world. Therefore this study was undertaken to assess microalbuminuria and serum C reactive protein (CRP) in non hypertensive AMI patients. The study was conducted in a group of 100 subjects consisting of 50 age and sex matched healthy control and 50 diagnosed cases of non hypertensive acute myocardial infarction (AMI) patients. There was a significant increase in level of microalbuminuria and serum CRP in non hypertensive AMI patients compared to healthy control. This study shows that microalbuminuria and serum CRP are useful biochemical parameter in non hypertensive acute myocardial infarction patients.