INTERNATIONAL JOURNAL OF ANATOMY PHYSIOLOGY AND BIOCHEMISTRY

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Authors: Vagga A, Meshram A, Anjankar A

Background: Sudarshan kriya yoga (SKY) is a unique breathing process advocated by The Art of Living foundation, Bangalore, India. Yogic breathing exercises decreases lipid peroxidation and improves antioxidant status in blood. This study aims to evaluate lipid peroxidation markers Malondialdehyde (MDA) and nitric oxide (NO) together with total antioxidant capacity (TAC) in fibrocystic breast disease patients. Method: Lipid peroxidation markers i.e. Malondialdehyde (MDA) and nitric oxide (NO) together with total antioxidant capacity (TAC) were evaluated using spectrophotometer (Elico Company) in serum of 30 fibrocystic breast disease patients with routine treatment (control group) and 30 fibrocystic breast disease patients with routine treatment along with sudarshan kriya yoga (SKY) (study group). Blood samples were collected from study group after 7 days of regular practice of sudarshan kriya yoga (SKY). Result: Serum MDA and NO were significantly decreased (p<0.001) with concomitant elevation levels of TAC in study group when compared to control group (p<0.001). Relationship between lipid peroxidation markers i.e. MDA and NO with total antioxidant capacity TAC were inversely related in both groups. Conclusion: Sudarshan kriya yoga practice may improve natural defense system/mechanism and decreases efficacy of oxidative stress in fibrocystic breast disease. However further extensive and long term studies to be done to prove these findings and understand the basic mechanism involved.