European Journal of Medicine

61-71

Authors: Georgi Gluhchev, Ignat Ignatov, Yuliana Pesheva

Shungite is amorphous, uncrystallized, fullerene analogous carbon containing natural mineral. Shungite carbon is a fossilized organic material of sea bottom Precambrian sediments of high level of carbonization containing the fullerene-like regular structures. Shungite got its name after the village of Shunga in Karelia (Russian Federation), located on the shore of Onezhskoe Lake, where is located Zazhoginsky deposit. The total shungite reserves of Zazhoginsky deposit amount to approximately 35 million tons. The plant production capacity for the mining and processing of shungite makes up 200 thousand tons of shungite per year. We study the properties of shungite for purification of water and detoxification of human body. In the report the authors show the properties for purification of water. There are basic data for detoxification of human body with water solution of shungite.

83-96

Authors: Naina Mohamed Pakkir Maideen

Sulfonylureas are useful to treat type 2 diabetes patients. Apart from sulfonylureas, the patients with diabetes may use many other medications to treat various concomitant illnesses such as high blood pressure, higher lipids, infections, pain, etc. The probability of interactions increases with the number of drugs used concomitantly. Most of the adverse drug interactions of sulfonylureas result in hypoglycemia, which can be life threatening. Sulfonylureas are primarily metabolized by CYP2C9 enzyme, which paves the way for most of their pharmacokinetic drug interactions. Drugs inhibiting CYP2C9 enzyme are expected to elevate the plasma concentrations of sulfonylureas and subsequent hypoglycemic complications. Some drugs potentiate the hypoglycemic activity of sulfonylureas pharmacodynamically too. The prescribers and pharmacists must be aware of the adverse drug interactions of sulfonylureas to prevent hypoglycemic episodes.

3-12

Authors: Georgi Gluhchev, Dimitar Mehandjiev, Ignat Ignatov, Stoil Karadzhov, Yuliana Pesheva, Atanas Atanasov

A two stage model of the physicochemical processes at the electrolysis of pure water is proposed. The presence of nascent hydrogen in the catholyte and nascent oxygen in the anolyte during the first stage explains the antioxidant properties of the catholyte and the strong biocidal action of the anolyte. In the second stage the nascent hydrogen and oxygen are combined into hydrogen and oxygen molecules, respectively. The comparison between their average energies with the average energy of the control sample of water shows an increase in the average energy of the catholyte and decrease in the average energy of the anolyte. This indicates that some changes in the structure of the activated water have occurred. There are results with method of Differential Non-equilibrium Water Spectrum (DNES) for alteration of energy of hydrogen bonds in catholyte and anolyte according control sample of water.

20-42

Authors: Ignat Ignatov, Yuliana Pesheva

We studied the mathematical model of interaction with water VITA intense of LavaVitae company (Austria). In this report are submitted data about the interaction of VITA intense with water, obtained by non-equilibrium (NES) and differential-equilibrium energy spectrum (DNES) of water. The average energy (∆EH... O) of hydrogen Н…O-bonds among individual molecules H2O after treatment of VITA intense with water measured by NES- and DNES-methods is ∆E=-0.0136±0.0011 eV for VITA intense. This result suggests the restructuring of ∆EH... O values among H2O molecules with a statistically reliable increase of local extremums in DNES-spectra. The research is performed for VITA intense, with study of pH and oxidative reduction potential (ORP). There is review of the effects of the chemical composition of VITA intense – anti-inflammatory, antioxidant etc. With methods NES we show the following effects – relaxing effect of nervous system, anti-inflammatory and inhibition of tumor cells. As results of these effects VITA intense has anti aging influence. The base of this influence is anti-inflammatory effect. This article deals with the review of the basic biophysical-biochemical and biological processes underlying the VITA intense. The author is studying their physical-chemical properties and biophysical and biological effects on human organism. Additionally, by using IR, NES, and DNES methods are investigated various samples of water from Bulgarian water springs: the melt water from Glacier Rosenlaui, Swiss Alps, as well as the human blood serum of people with excellent health and cancer patients between 50 and 70 years old. Other experiments were performed on a 1 % (v/v) solution of VITA intense in deionized water. As an estimation factor in NES and DNES was measured the values of the average energy of hydrogen bonds (∆EH...O) among H2O molecules in water samples, as well as a local extremums in the NES and DNES-spectra of various samples of water and the human blood serum at E = -0.1387 eV and λ = 8.95 μm. For a group of people in critical condition of life and patients with malignant tumors the greatest values of local extremums in IR-, DNES-spectra were shifted to lower energies relative to the control healthy group. Further we applied this method for calculation of percent distribution of H2O molecules in all studied water samples according to energies of hydrogen bonds ranged from (-0.08 to -0.1387 eV). It was shown that mountain water is among the most important factors for human longevity and human health. The variety of ions (K+, Na+, Ca2+, Mg2+, Mn2+, Fe2+, Fe3+, Zn2+, SO42-, Cl-, HCO3-, CO32-), the chemical-physical parameters (pH, electroconductivity) and the decreased content of deuterium in studied water samples renders beneficial effects of these types of water on human health. We are applying the conclusions for the effects of mountain water on human health and longevity as base for the conclusion on the effects of VITA intense. The base is also the results with methods NES and DNES on human serum and expected effects from VITA intense. VITA intense has negative oxidative reduction potential (ORP) and this is special property of this product for antioxidant effects again free radicals.

52-58

Authors: А.М. Ungurian, М.V. Dikal, K.A. Irynchina

The aim of the study was to establish objective parameters of the field of laser and incoherent radiation of different spectral ranges (UV, visible, IR) as a non-invasive optical method of interaction with different samples of biological tissues and fluids of patients to determine the dynamics of peritonitis and choosing the best personal treatment. The objects of study were selected venous blood plasma of children and rats, histological sections of rat intestine in the postoperative period. As diagnostic methods have been used ultraviolet spectrometry samples of blood plasma in the liquid state, infrared spectroscopy middle range (2.5–25 microns) dry residue of plasma polarization and laser diagnostic technique of thin histological sections of biological tissues.