European Journal of Medicine

118-123

Authors: Oksana G. Cherniukh, Maryana V. Dikal

The work deals with the analysis of the umbilical blood samples (120 samples) concerning the concentration of general protein and glucose as the main biological constants of newborns. There is no a reliable difference found between these indices while comparing groups with monocyesis and twin pregnancies. Possible correlation interrelation of certain biochemical indices in newborns during early postnatal period was examined (54 samples). In addition, changes of the examined biochemical indices were followed in the course of time in 19 newborns concerning the comparison of umbilical and venous blood.

139-149

Authors: Sribas Goswami, Manjari Sahai

Adolescence is the period of physical and psychological development from the onset of puberty to maturity. The World Health Organization defines an adolescent as a person between ages 10 and 19 years. A dramatic shift in thinking from concrete to abstract gives adolescents a whole new set of mental tools, to analyze situations logically in terms of cause and effect, appreciate hypothetical situations, evaluate alternatives, introspection, decision making and cognitive abilities. Adolescents experience intense physical, psychological changes as they make transition from childhood to adulthood. This period of transition is the most vulnerable time. Adolescents are at risk of developing behavioral problems like school failure and drop outs, substance abuse, delinquency and violence, sexually transmitted diseases, unwanted pregnancies, domestic violence, stress and depression and risk-taking behaviour. It is the responsibility of the society to utilize this period constructively through education, counseling, mass media, awareness programmes and address the reproductive health needs of adolescents. The present study analyzes the psychosocial risk status and knowledge of reproductive health in adolescents in Raipur city. The study recommends implementation of provisions by government to provide continuous education and economic security for adolescents. Programmes like age-appropriate reproductive health curriculum should be introduced in schools and colleges with counseling facilities at school and primary health care levels.

155-169

Authors: Nozim N. Khoshimov, Guli M. Raimova, Kabil E. Nasirov, Valentina I. Vinogradova

Modeling of sharp alcoholic intoxication induced animal 6 mg/kg of 50-70% ethanol by introduction. On this background studied effects of N-metilsitizin alkaloids and a desoxypeganin on ADP-induced aggregation of platelets and level of intracellular Ca2+ in the synaptosomes of a brain of rats. The obtained data render that the inhibiting effect of N-metilsitizin alkaloids and a desoxypeganin on ADP-induced aggregation of platelets is connected with oppression of a gain of cytoplasmatic concentration of Ca2+ from depot of platelets. Thus, N-metiltsitizin alkaloids and desoxypeganin block a gain of level of intracellular Ca2+ at the expense of increase in Ca2+ EPR pool, provoked by ethanol. N-metiltsitizin doesn’t compete with a glutamate for a binding site. Perhaps, action of N-metiltsitizin is caused by interaction with ionic channels of NMDA receptors. The neuronal of the receptors involved in the mechanisms which are the cornerstone of AAS (including convulsive attacks) and effectively to stop to possibility of application of N-metilsitizin in regulation of dihydropyridine-sensitive calcic channels of the main subtypes them. It is shown that the possible competition between desoxypeganin and a glutamate for a site of binding of regulation of opening of ionic channels. Desoxypeganin directly doesn't affect calcic canals of a NMDA receptor. Perhaps, desoxypeganin like a glutamate causes overexcitation of NMDA receptors.

180-186

Authors: Goh Bee See, Nurfarissa binti Hussin

Objective: This is a series of five cases of branchial anomalies which were diagnosed and treated in a span of six years in the Department of Otorhinolaryngology, Head & Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre (UKMMC). The main objective of this article is to highlight the use of endoscopic electrocautery in the management of branchial fistula. Case report: five cases were reported of the age group between 11 months old to 16 years who presented with an intermittent mucoid discharge from an external opening in the neck since birth and three cases were on the left side and the other two cases were bilateral fistula. Direct laryngoscopy under general anaesthesia was done as part of diagnostic and therapeutic management for the patients. Conclusion: Endoscopic electrocautery is a safe method and appears to be an effective alternative to open excision for branchial fistula.