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Synthesis of 1,3-Bis (N-Substitutedamidinothiocarbamido)-Thiocarbimides
Authors: SHELKE M.E.
Number of views: 454
Amidinothiocarbamides and their derivatives possess various pharmaceutical,
industrial, medicinal and agricultural values1-4. Intraction of different thiocarbamides
and substituted cyanamides were carried out to synthesised respective substituted
thiocarbamides, bis-foramidino sulphide, amidinothiocarbamides (salt) and their
derivatives.5-8 Amidinothiocarbamides and their derivatives were successfully cyclised
into respective Hector’s bases, thiadiazines, dithiazines, thiadiazolidines, s-triazines and
pyrimidines by using different reagent and different reaction conditions. 9-14 So it was
thought interesting to synthesis yet new series of 1,3-bis (Nsubstitutedamidinothiocarbamido)-
thiocarbamides.(2) which may posses different
pharmaceutical, industrial, medicinal, agricultural important which may be further
cyclise to synthesis yet new series of 5 and 6 membered hetercyclic compounds.The
structure of all these compounds were established on the basis of elemental analysis ,IR
and PMR spectral data.