The Journal of V. N. Karazin Kharkiv National University. Series «Medicine»

5-9

Authors: O.N. Pobelensky

Experimental investigations of transplantation effect under the capsule of kidney of the newborn piglet’s pancreas cryopreserved microfragments on glycemia level and the indices of lipid peroxidation in rats with alloxan diabetes were carried-out in the work.

13-17

Authors: O.H. Bazarynsky

The quantitative and qualitative evaluation of uroflowmetrograms in 38 patients aged 23-48 years suffering from chronic abacterial prostatitis with dysuric syndrome had been carried out. Five basic and two complementary abnormal schematic types of dysuria were established by descriptive statistics. The results of study demonstrated that uroflowmetry is one of the most demonstrative methods of diagnostics in mentioned patients and has to become an integral part of chronic abacterial prostatitis with dysuric syndrome patients’ examination algorithm, as it is capable to determine the pathophysiologic foundation of symptoms and to clarify the essence of detrusive sphincteral dyssynergy and contributing in the choice of adequate management.

22-25

Authors: V.V. Boyko, E.D. Khvorosto, S.V. Sushkov

The experience of 89 laparoscopic vagotomies performed during 7 years is presented by avthor. Original method of laparoscopic vagotomy (declarative patent N 33508A) was used in 26 patients. The following conclusions were made: laparoscopic vagotomy is the treatment of choice in Helicobacter pylori – negative complicated duodenal ulcers that do not resolve under medical treatment during 10 weeks. Laparoscopic cryovagotomy is optimal measure for the decrease of acid production withour disturbances of gastric motor function. Laparoscopic cryovagotomy is recommended in patients with Helicobacter pylori – negative recurrent and complicated duodenal peptic ulcer due to its simple technique and efficiacy during follow – up.

30-33

Authors: B.P. Vvedensky

Resulted etiopathogenetical data of clinic, clinic, diagnostics, conservative medical treatment in arthroscopic and restoration interferences at deforming artroze of knee-joint.

37-41

Authors: R.N. Grynyov

Author presents an experience of the surgical treatment of 82 patients with different types of the Mirizzi syndrome. Most informative in diagnostics of the Mirizzi syndrome were sonography – 67,1% and endoscop-ic retrograde cholangiopancreatography – 58,5%.At a suspicion on Mirizzi syndrome all patients were performed laparoscopic intraoperative cholangiography, herewith diagnostic value of this method approached to 100%. The оperation of the choice in patients with syndrome Mirizzi type І was laparoscopic cholecystectomy, by impossibility of laparoscopic operations and at syndrome Mirizzi type ІІ preference was given to traditional cholecystectomy with drainaging of choledoch, or to Roux's hepaticojejunostomy.

44-48

Authors: Yu.B. Zakharchenko

The results of treatment the 34 patients with the acute purulent cholangitis was analysed. There were 9 men (26,4%) and 25 women (73,6%) in the age for 43 to 87. On the entrance those patients to the clinic their general condition were heavy, but some of them had middle weight condition. The possibility violation of the gall-ducts on the level of common bile duct were conditioned with: the big stones have 18 patients (52,9%), which defied to endoscopic choledocholithotraction; strictures of the ducts have 8 patients (24,7%); combination of choledocholithiasis with the strictures have 5 patients (14,7%); combination of the chole¬do-cholithiasis with parapapillar diverticulum have 3 patients (8,8%). The diagnostic program conclude of the clinical and laboratories methods investigations, ultrasound scanning, endofibroscopic investigation the top past of the gastro-intestinal tract, endoscopic retrograde cholangiopancreatography, cholangiomanometry, bacteriological cheek up of the bile. The treatment program included: the standard infussional therapy of acute cholangitis and the obstructive jaundice; the endoscopic sphincterotomy with following nasobiliar drainage; the landmark endocholangial leading physiological solution. As the results of the treatment all pa-tients with acute obstructive purulent cholangitis in all cases were mixed in the period of 4-9 days after the treatment starting, with were definite by the clinical flowing and verified by the dates of laboratorical cheek up methods. All of these allowed to fulfil the radical surgical intervention on the common bile duct with the least risk for the patient. There was no lethal outcome.

51-56

Authors: S.A. Morozov, A.V. Tsaryov

Аn experience of treatment of 160 patients with a syndrome of diabetic foot is submitted; results of inspection, tactics of treatment and volume of operative interventions are considered.

59-62

Authors: V.І. Rusin, Yu.А. Levchak, V.V. Rusin, F.V. Gorlenko

In present study the results of surgical treatment of 60 patients with chronic venous insufficiency of the lower limbs are submitted. Alongside with conventional interference – simple venectomy by Babcock, authors also used subfascial endoscopic perforance ligation and cathether sclerotherapy of the main shaft of the saphenic vein. In the group of patients, in treatment of which one miniinvasive methods were used, there were no purulent complications. Also the introduction in clinical practice of the SEPS method in combination with a distal saphen trunks scleroobliteration shortens the stay of patients in hospital and substantially decreases economic expenses on their treatment. The further study of subfascial endoscopic perforance ligation and cathether sclerotherapy of the main shaft of the saphenic vein capabilities in treatment of other stages of chronic venous insufficiency is necessary.

69-71

Authors: V.O. Siplivy, G.D. Petrenko, S.M. Teslenko, A.G. Gus, O.G. Petunin, S.V. Grinchenko

Are shown the results of laparoscopic cholecystectomy in 145 patients with acute destructive cholecystitis. Is offered the dissection of gallbladder wall for better identification of triangle Callot structures in oedematic hepatoduodenal ligament. For simplification of operative measure are constructed raspatories and conductors of tubular drainages. Are designed the rational schemes of a drainage of abdominal cavity. All this has allowed to decrease bed-day up to 7,2, and quantity of complications up to 1,3%.

75-78

Authors: A.I. Tsivenco, M.S. Тоmіn

In work gives the analysis of disease, efficiency of methods of diagnostics and modern treatment colorectal cancer is. The first experience of application of a ultrasonic (harmonic) scalpel is submitted at traditional and laparoscopic interventions concerning a colon cancer and rectum. Results of application autovaccine in complex treatment of patients with colorectal cancer.

83-86

Authors: E.P. Yakovtzov, A.E. Gavrikov, A.V.Babalyan

In article results of research of hormones at patients with cholelithiasis of various age are submitted. At elderly and senile age persons it is revealed hormonal dysbalance with decrease in melatonin concentration. The conclusion about expediency of use of synthetic analogue of melatonin – vita-melatonin in a complex of preoperative preparation and postoperative treatment at laparoscopic cholecystectomy is made.

90-94

Authors: V.G. Psarheva

We examined 69 patients with chronic heart failure (HF) caused by ischemic heart disease. It was examined endothelial function such as endothelin-1, cAMP, cGMP and 6-keto-PGF1α contens. It was determined that HF has high endothelin-1 level, wich is most in HF IV functional classes, and has low cGMP level. Enalapril and losartan inhibit the activity of RAAS function.

101-107

Authors: N.I. Yabluchansky, H.G.Datsenko

In the grounds of complex examination of 300 patients with essential arterial hypertension the mathematical pattern of prognosis the results of double-component antihypertention therapy by enalaprili maleatum (10 mg per day) and hydrochlortiasidum (25 mg per day) was worked out. Accounted the initial meanings of middle daily heart rate (HR) non-modified risk factors (the blood pressure (BP) level, the type of somato-vagal balance and the type of left ventricular geometry). It was started, that good results of lowering BP in the double-component antihypertentional therapy by enalaprili maleatum (10 mg per day) and hydrochlortiasidum (25 mg per day) correspond the probabily of 70%, setisfed results of normalisation - the probabily of 50-70%, dissetistole results - the probabily of less then 50%. The double-component antihypertentional therapy by enalaprili maleatum (10 mg per day) and hydrochlortiasidum (25 mg per day) is shown to the patients with the probability of BP normalization more than 70%.